The chronobiology of blood pressure in pregnancy

Pregnancy Hypertens. 2018 Apr:12:104-109. doi: 10.1016/j.preghy.2018.04.002. Epub 2018 Apr 7.


This review summarizes the literature to date on the subject of the chronobiology of blood pressure in pregnancy, and more specifically, in the common disease state of high blood pressure in pregnancy or preeclampsia. While the guidelines for treating hypertension in pregnancy use absolute measures to start treatment, they do not take into account the important rhythms of hypertension including nighttime and daytime readings. These variations are likely to have strong impacts on pregnancy outcomes, risk and long-term hypertension risk.

Keywords: Blood pressure; Chronobiology; Circadian; Hypertensive disorders pregnancy; Preeclampsia; Pregnancy.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Blood Pressure Monitoring, Ambulatory
  • Blood Pressure* / drug effects
  • Circadian Rhythm*
  • Female
  • Humans
  • Pre-Eclampsia / diagnosis
  • Pre-Eclampsia / drug therapy
  • Pre-Eclampsia / mortality
  • Pre-Eclampsia / physiopathology*
  • Pregnancy
  • Risk Factors
  • Time Factors
  • Treatment Outcome


  • Antihypertensive Agents