Recent Advances in the Catalytic Enantioselective Reactions of para-Quinone Methides

Abstract

In recent years, the catalytic enantioselective reactions of p-QMs have drawn much attention, because of their distinctive reactivities. As such, a variety of chiral catalytic systems have been developed. This Focus Review describes the reactions of p-QMs according to the chiral catalyst system used, with the aim of provide the first complete picture of the exciting developments in this field. Special emphasis is placed on recent work regarding their reaction mechanisms.

Keywords: annulation; asymmetric catalysis; conjugate addition; para-quinone methides; synthetic methods.