Osseous Rosai-Dorfman Disease Presenting as a Solitary Lesion of the Distal Radius

J Hand Surg Am. 2019 Jan;44(1):70.e1-70.e5. doi: 10.1016/j.jhsa.2018.03.019. Epub 2018 Apr 17.


Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a rare entity in which bone involvement occurs in less than 5% to 10% of patients and skeletal cases are usually multifocal. Extranodal solitary lesions of bone without nodal involvement or additional clinical manifestations are exceedingly rare. We present the clinical course and management of a 34-year-old African American woman who presented with the disease as a solitary lesion of the distal radius.

Keywords: Distal radius; Rosai–Dorfman disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Histiocytosis, Sinus / diagnostic imaging*
  • Histiocytosis, Sinus / surgery*
  • Humans
  • Magnetic Resonance Imaging
  • Radiography
  • Radius / diagnostic imaging*
  • Radius / surgery*