Muscle-ultrasound evaluation in healthy pediatric subjects: Age-related normative data

Muscle Nerve. 2018 Aug;58(2):245-250. doi: 10.1002/mus.26151. Epub 2018 Jun 15.

Abstract

Introduction: The muscle ultrasound examination (MUS) is a noninvasive and inexpensive technique for evaluating neuromyopathies. Standardized MUS normative data are incomplete in pediatric subjects.

Methods: We performed a MUS study with 120 healthy children (59 males; mean age, 10.44 years; age range, 2-16 years). We measured the width and the echogenicity bilaterally in the following muscles: biceps brachii and brachialis, brachioradialis, forearm-flexors, rectus femoris and vastus intermedius, tibialis anterior, extensor hallucis longus, lateral and medial gastrocnemius.

Results: The muscle thickness increased with age for all muscles. Confidence limits were set for each age group muscle width. Echogenicity increased with age only in some muscles.

Discussions: Our MUS study provides new data on physiological muscle structural changes in healthy children to address the limited available references in this age group. Muscle Nerve 58: 245-250, 2018.

Keywords: child; diagnosis; muscle imaging; muscle ultrasound; neuromuscular diseases; ultrasonography.

MeSH terms

  • Adolescent
  • Age Factors
  • Aging / physiology
  • Child
  • Child, Preschool
  • Female
  • Healthy Volunteers
  • Humans
  • Male
  • Muscle, Skeletal / diagnostic imaging*
  • Muscle, Skeletal / growth & development
  • Reference Values
  • Ultrasonography / standards*