Pulmonary hypertension due to unclassified interstitial lung disease in a Pembroke Welsh corgi

J Vet Med Sci. 2018 Jun 29;80(6):939-944. doi: 10.1292/jvms.17-0716. Epub 2018 Apr 23.


A 12 year-old intact male Pembroke Welsh corgi weighing 10.8 kg was presented for evaluation of a 3-month history of dyspnea, and a 1-week history of exercise intolerance and anorexia. Severe hypoxemia (PaO2 56 mmHg), diffuse lung alveolar infiltration, and severe pulmonary hypertension (PH) (tricuspid regurgitation pressure gradient was 81 mmHg) were identified. A tentative diagnosis of severe PH due to lung disease or pulmonary thromboembolism was made and treated intensively. After 5 days of hospitalization, the dog died despite oxygen supplementation and anticoagulant therapy. This dog was diagnosed as unclassified interstitial lung disease based on histopathological findings.

Keywords: canine; echocardiography; respiratory disease.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Blood Gas Analysis / veterinary
  • Dog Diseases / diagnosis*
  • Dogs
  • Fatal Outcome
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / veterinary*
  • Lung Diseases, Interstitial / diagnosis
  • Lung Diseases, Interstitial / veterinary*
  • Male
  • Sildenafil Citrate / therapeutic use


  • Sildenafil Citrate