How human microbiome talks to health and disease

Eur J Clin Microbiol Infect Dis. 2018 Sep;37(9):1595-1601. doi: 10.1007/s10096-018-3263-1. Epub 2018 Apr 22.

Abstract

Microbes are ubiquitous in the human body. They usually live in communities, and each of these communities has a distinct taxonomical structure. Due to its close relationship with human health and disease, the human microbiome has received great attention and is probably considered to be the most valuable biomarker in preventing and solving human diseases. In this paper, we first review the value of the human microbiome. Then, we focus on the role of the human microbiome in influencing human health and disease. Furthermore, we intensively discuss the relationship between intestinal microbiota and cancer therapy. Finally, we briefly summarize the significance of the human microbiome based on the development of sequencing and bioinformatic techniques.

Keywords: Cancer therapy; Health and disease; Human microbiome; Intestinal microbiota; Technique.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Computational Biology
  • Disease / etiology*
  • Gastrointestinal Microbiome / genetics
  • Health*
  • Humans
  • Microbiota / genetics*
  • Mouth / microbiology
  • Neoplasms / therapy*
  • Skin / microbiology

Substances

  • Biomarkers