Phenotypic diversity of the CD45 antigen and its relationship to function

Immunol Suppl. 1988:1:3-5.

Abstract

Monoclonal antibodies (mAbs) have identified further heterogeneity within the major CD4 and CD8 T-lymphocyte subsets. Antibodies to different polypeptides of the CD45 complex separate two largely non-overlapping subsets that may represent stages in the maturation of T cells or separate functionally distinct subsets.

MeSH terms

  • Animals
  • Antigens, Differentiation / analysis*
  • Antigens, Differentiation / immunology
  • Cell Line
  • Chemical Phenomena
  • Chemistry
  • Histocompatibility Antigens / analysis*
  • Histocompatibility Antigens / immunology
  • Humans
  • Leukocyte Common Antigens
  • Leukocytes / immunology
  • Mice
  • Rats
  • T-Lymphocytes / classification*
  • T-Lymphocytes / immunology

Substances

  • Antigens, Differentiation
  • Histocompatibility Antigens
  • Leukocyte Common Antigens