The effect of mastication on food intake, satiety and body weight

Physiol Behav. 2018 Sep 1;193(Pt B):242-245. doi: 10.1016/j.physbeh.2018.04.027. Epub 2018 Apr 21.


As mastication is the major component of the oral processing of solid foods a better understanding of its influence on ingestion, digestion and metabolism may lead to new approaches to improve health. A growing number of studies provide evidence that mastication may influence energy balance through several routes: activation of histaminergic neurons, reducing eating rate, altered digestion kinetics, and changes in macronutrient availability. Indeed, accumulating evidence indicates that increasing the number of masticatory cycles before swallowing reduces food intake and increases satiety. However, while slowing eating rate has been shown to limit weight gain in children and adolescents it is not clear that slowing eating rate by increasing the number of masticatory cycles or slowing mastication rate is a viable method to aid weight management ([10], [15]). Further research is required to determine the influence of mastication on energy balance and how it could be manipulated to aid weight management. This narrative review will provide a brief overview of the effect of mastication on food intake, satiety and body weight.

Keywords: Appetite; Body weight; Mastication; Oral processing.

Publication types

  • Review

MeSH terms

  • Animals
  • Body Weight* / physiology
  • Feeding Behavior / physiology
  • Humans
  • Mastication* / physiology
  • Satiation* / physiology