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. 2018 Jan 1;2018:bay023.
doi: 10.1093/database/bay023.

miRwayDB: A Database for Experimentally Validated microRNA-pathway Associations in Pathophysiological Conditions

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Free PMC article

miRwayDB: A Database for Experimentally Validated microRNA-pathway Associations in Pathophysiological Conditions

Sankha Subhra Das et al. Database (Oxford). .
Free PMC article

Abstract

http://www.mirway.iitkgp.ac.in.

Figures

Figure 1.
Figure 1.
The schematic representation of miRwayDB.
Figure 2.
Figure 2.
Search output of miRwayDB.
Figure 3.
Figure 3.
Distribution of pathophysiological conditions in miRwayDB.
Figure 4.
Figure 4.
MicroRNA-21 associated pathophysiological conditions (A) and pathways (B).
Figure 5.
Figure 5.
PI3K-Akt signaling pathway associated pathophysiological conditions (A) and dysregulated genes (B).
Figure 6.
Figure 6.
Top 3 pathways with highest miRNA scores (A) and gene scores (B); and top 3 miRNAs with highest gene scores (C) and pathway scores (D).

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References

    1. Pasquinelli A.E. (2012) MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet., 13, 271–282. - PubMed
    1. Friedman J.M., Jones P.A. (2009) MicroRNAs: critical mediators of differentiation, development and disease. Swiss Med. Wkly., 139, 466–472. - PMC - PubMed
    1. Jeong D., Kim J., Nam J. et al. (2015) MicroRNA-124 links p53 to the NF-kappaB pathway in B-cell lymphomas. Leukemia, 29, 1868–1874. - PubMed
    1. Xie L., Ushmorov A., Leithauser F. et al. (2012) FOXO1 is a tumor suppressor in classical Hodgkin lymphoma. Blood, 119, 3503–3511. - PubMed
    1. Chen H.H., Huang W.T., Yang L.W. et al. (2015) The PTEN-AKT-mTOR/RICTOR pathway in nasal natural killer cell lymphoma is activated by miR-494-3p via PTEN but inhibited by miR-142-3p via RICTOR. Am. J. Pathol., 185, 1487–1499. - PubMed

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