Under one roof: identification, evaluation, and treatment of chronic hepatitis C in addiction care

Addict Sci Clin Pract. 2018 Apr 25;13(1):10. doi: 10.1186/s13722-018-0111-7.

Abstract

For over a decade, the vast majority of new hepatitis C virus (HCV) infections have been among young people who inject drugs (PWID). Well-characterized gaps in chronic HCV diagnosis, evaluation, and treatment have resulted in fewer than 5% of PWID receiving HCV treatment. While interferon-based treatment may have intentionally been foregone during part of this time in anticipation of improved oral therapies, the overall pattern points to deficiencies and treatment exclusions in the health care system. Treatment for HCV with all-oral, highly effective direct-acting antiviral medication for 12 weeks or less is now the standard of care, putting renewed focus on effective delivery of care. We describe here both the need for and process of chronic HCV care under the roof of addiction medicine.

Keywords: Chronic hepatitis C; Cirrhosis; Continuity of care; Hepatitis C epidemiology; Hepatitis C treatment; Opioid use disorder; Project ECHO; Treatment cascade.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Hepatitis C, Chronic / diagnosis
  • Hepatitis C, Chronic / drug therapy*
  • Hepatitis C, Chronic / epidemiology*
  • Humans
  • Mass Screening / methods
  • Substance Abuse Treatment Centers / organization & administration*
  • Substance Abuse, Intravenous / epidemiology*
  • Substance Abuse, Intravenous / therapy*
  • Systems Integration

Substances

  • Antiviral Agents