Meta-analysis of Robot-assisted Versus Laparoscopic Surgery for Rectal Cancer

In Vivo. 2018 May-Jun;32(3):611-623. doi: 10.21873/invivo.11283.

Abstract

Background/aim: A meta-analysis was conducted to evaluate and compare the short- and long-term outcomes of robot-assisted (RAS) and conventional laparoscopic surgery (LAS) for rectal cancer.

Materials and methods: We searched MEDLINE for relevant papers published between 2010 and December 2017 by using specific search terms. We analyzed outcomes over short- and long-term periods.

Results: We identified 23 papers reporting results that compared RAS for rectal cancer with LAS. Our meta-analysis included 4,348 patients with rectal cancer; 2,068 had undergone RAS, and 2,280 had undergone LAS. In the short- and long-term period, 27 and 7 outcome variables were examined, respectively. RAS for rectal cancer was significantly associated with a greater operative time and a lower conversion rate to open surgery in the short-term, and results in almost similar outcomes in the long-term, compared to LAS.

Conclusion: RAS may be an acceptable surgical treatment option compared to LAS for rectal cancer.

Keywords: Rectal cancer; laparoscopic surgery; meta-analysis; robot-assisted surgery.

Publication types

  • Meta-Analysis

MeSH terms

  • Blood Loss, Surgical
  • Chemoradiotherapy / methods
  • Clinical Trials as Topic
  • Humans
  • Laparoscopy* / adverse effects
  • Laparoscopy* / methods
  • Neoadjuvant Therapy
  • Operative Time
  • Postoperative Complications
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Rectal Neoplasms / therapy
  • Robotic Surgical Procedures* / adverse effects
  • Robotic Surgical Procedures* / methods
  • Treatment Outcome