KO tBu-Promoted C4 Selective Coupling Reaction of Phenols and [60]Fullerene: One-Pot Synthesis of 4-[60]Fullerephenols under Transition-Metal-Free Conditions

Fei Li; Jun Xuan; Shu Zhang; Boxiang Liu; Jianxiao Yang; Kaiqing Liu; Dandan Liu; Qiong Zhang; Hongping Zhou; Jieying Wu; Yupeng Tian

doi:10.1021/acs.joc.8b00261

KO ^tBu-Promoted C4 Selective Coupling Reaction of Phenols and [60]Fullerene: One-Pot Synthesis of 4-[60]Fullerephenols under Transition-Metal-Free Conditions

J Org Chem. 2018 May 18;83(10):5431-5437. doi: 10.1021/acs.joc.8b00261. Epub 2018 May 4.

Authors

Fei Li^{1

2}, Jun Xuan¹, Shu Zhang¹, Boxiang Liu¹, Jianxiao Yang¹, Kaiqing Liu², Dandan Liu¹, Qiong Zhang¹, Hongping Zhou¹, Jieying Wu¹, Yupeng Tian¹

Affiliations

¹ Department of Chemistry, Key Laboratory of Functional Inorganic Materials of Anhui Province , Anhui University , Hefei 230039 , P. R. China.
² Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , P. R. China.

PMID: 29696979
DOI: 10.1021/acs.joc.8b00261

Abstract

A KO ^tBu-promoted direct coupling reaction of phenols and [60]fullerene was disclosed. The reaction occurs exclusively at the C4-position of phenols with high regioselectivity and provides an efficient and inexpensive manner to various 4-[60]fullerephenols in good yields. The electrochemical properties of the products render the method attractive and valuable.

Publication types

Research Support, Non-U.S. Gov't