Randomized, double-blind, placebo-controlled study vs data in the daily practice using linaclotide in patients with irritable bowel syndrome with constipation

Affiliations

• ¹ Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
• ² Department of Gastroenterology, Yokohama City University, Yokohama, Japan.
• ³ Shiga University of Medical Science, Ohtsu, Japan.
• ⁴ Japan-Asia Clinical Development 2, Development, Astellas Pharma Inc., Tokyo, Japan.
• ⁵ Japan-Asia Data Science, Development, Astellas Pharma Inc., Tokyo, Japan.
• ⁶ Ironwood Pharmaceuticals Inc., Cambridge, MA, USA.
• ⁷ Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.