A systematic review and meta-analysis of comparison between autologous costal cartilage and alloplastic materials in rhinoplasty

J Plast Reconstr Aesthet Surg. 2018 Aug;71(8):1164-1173. doi: 10.1016/j.bjps.2018.03.017. Epub 2018 Apr 11.

Abstract

Background: Both autologous costal cartilage (ACC) and alloplastic materials are widely used in rhinoplasty. However, there is controversy regarding which material can offer the ideal outcome and fewer complications.

Objective: The authors review current literature to evaluate complication and satisfaction rates with different materials used in rhinoplasty.

Methods: A comprehensive literature search of articles was conducted in Embase and PubMed published through April 14, 2017. We included only articles that used ACC, silicone, Medpor, Gore-Tex, or a combination of autologous and alloplastic materials in rhinoplasty. The primary outcomes analyzed were complications and postoperative satisfaction. After data extraction, meta-analysis using the random effect model was performed to summarize outcome parameters among different implant types.

Results: Fifty-three articles met inclusion criteria and were included in the meta-analysis. The overall complication rate of ACC was 14%, which was higher than that of other implants. However, ACC was more commonly used in revision rhinoplasty. Medpor was associated with low overall complication rates (6%) and good aesthetic and functional outcomes.

Conclusions: Our analysis of available evidence suggests that ACC is preferred in revision rhinoplasty, which may explain its association with higher complication rates. In primary rhinoplasty, Medpor offered versatility in addition to low complication rates and good aesthetic and function outcomes. But its potential dramatic damage to the nasal tissue made secondary surgery extremely difficult. Our findings were limited by lack of high-quality evidence. Future studies with rigorous study design for head-to-head comparisons and longer follow-up are needed to establish clear guidelines for choosing the appropriate rhinoplasty graft material.

Keywords: Autologous costal cartilage; Gore-Tex; Medpor; Rhinoplasty; Silicone.

Publication types

  • Meta-Analysis
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Systematic Review

MeSH terms

  • Biocompatible Materials*
  • Costal Cartilage / transplantation*
  • Humans
  • Polyethylenes*
  • Prostheses and Implants
  • Rhinoplasty / methods*
  • Transplantation, Autologous

Substances

  • Biocompatible Materials
  • Medpor
  • Polyethylenes