Trichilemmal Cyst: Clinical and Sonographic Features

J Ultrasound Med. 2019 Jan;38(1):91-96. doi: 10.1002/jum.14666. Epub 2018 Apr 30.

Abstract

Objectives: In this study, we retrospectively reviewed the clinical and sonographic features of patients with trichilemmal cysts.

Methods: Sonographic findings of 54 cases of trichilemmal cysts were retrospectively analyzed from 50 patients, including 4 cases of proliferating trichilemmal cysts. Associated factors of internal calcification-positive cases were also evaluated.

Results: The mean age of the 50 patients was 43.4 years (range, 15-80 years) and the female-to-male ratio was 1.3. Overall, 68% of the trichilemmal cysts in the 54 lesions were located in the scalp, and 15% were located in the extremities. All 54 lesions were preoperatively examined by sonography and showed well-defined, oval-shaped structures located in subcutaneous soft tissues close to the dermis. Of the 54 lesions, 72% were hypoechoic masses, 89% were heterogeneous, and 65% had internal calcification. Among the internal calcification-positive cases, the mean age of the patients was 43.4 years, and the female-to-male ratio was 0.6. Of these lesions, 83% were located in the scalp. We did not find any significant association between calcification, age, or sex (P = .993 and P = .99); however, lesions present in the scalp were significantly associated with internal calcification (P = .005). 81% of the 54 lesions displayed posterior enhancement. but the color Doppler sonography of all lesions revealed no vascularization.

Conclusions: Trichilemmal cysts should be considered to diagnose of well-defined, hypoechoic lesions with internal calcification and posterior sound enhancement in the subcutaneous soft tissues of the scalp or extremities upon sonography.

Keywords: clinical features; diagnosis; trichilemmal cyst; ultrasonography.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Diagnosis, Differential
  • Epidermal Cyst / diagnostic imaging*
  • Extremities / diagnostic imaging
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Scalp / diagnostic imaging
  • Ultrasonography / methods
  • Young Adult