Improving diabetes care among patients with severe mental illness: A systematic review of the effect of interventions

Prim Care Diabetes. 2018 Aug;12(4):289-304. doi: 10.1016/j.pcd.2018.03.008. Epub 2018 Apr 27.


Background and aim: Individuals with severe mental illness (SMI) who suffer from type 2 diabetes (T2DM) are likely to be sub-optimally treated for their physical condition. This study aimed to review the effect of interventions in this population.

Methods: A systematic search in five databases was conducted in July 2017.

Results: Seven studies on multi-faced interventions were included. These comprised nutrition and exercise counselling, behavioural modelling and increased disease awareness aiming to reduce HbA1c, fasting plasma glucose, body mass index and weight.

Conclusion: Non-pharmacologic interventions in individuals with SMI and T2DM could possibly improve measures of diabetes care, although with limited clinical impact.

Keywords: Diabetes; Intervention; Severe mental illness; Systematic review; T2DM.

Publication types

  • Research Support, Non-U.S. Gov't
  • Systematic Review

MeSH terms

  • Adult
  • Comorbidity
  • Delivery of Health Care, Integrated*
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / psychology
  • Diabetes Mellitus, Type 2 / therapy*
  • Female
  • Health Knowledge, Attitudes, Practice
  • Health Status
  • Healthy Lifestyle
  • Humans
  • Male
  • Mental Disorders / diagnosis
  • Mental Disorders / epidemiology
  • Mental Disorders / psychology
  • Mental Disorders / therapy*
  • Mental Health
  • Middle Aged
  • Patient Compliance
  • Prognosis
  • Quality Improvement*
  • Quality Indicators, Health Care*
  • Risk Factors
  • Self Care
  • Severity of Illness Index