The Most Twisted Amide: Structure and Reactions

Anthony J Kirby; Igor V Komarov; Peter D Wothers; Neil Feeder

doi:10.1002/(SICI)1521-3773(19980403)37:6<785::AID-ANIE785>3.0.CO;2-J

The Most Twisted Amide: Structure and Reactions

Angew Chem Int Ed Engl. 1998 Apr 3;37(6):785-786. doi: 10.1002/(SICI)1521-3773(19980403)37:6<785::AID-ANIE785>3.0.CO;2-J.

Authors

Anthony J Kirby¹, Igor V Komarov¹, Peter D Wothers¹, Neil Feeder¹

Affiliation

¹ University Chemical Laboratory, Cambridge CB2 1EW (UK), Fax: (+44) 1223-336-362.

PMID: 29711382
DOI: 10.1002/(SICI)1521-3773(19980403)37:6<785::AID-ANIE785>3.0.CO;2-J

Abstract

The title amide 1 behaves more like a ketone-up to a point! The crystal structure of this (90°) twisted amide shows a pyramidal nitrogen atom next to a planar carbonyl group.

Keywords: Amides; Cage compounds; Ketones; Stereoelectronic effects.