From Substrate to Transition State Analogues: The First Potent Inhibitor of Sialyltransferases

Angew Chem Int Ed Engl. 1999 May 17;38(10):1379-1380. doi: 10.1002/(SICI)1521-3773(19990517)38:10<1379::AID-ANIE1379>3.0.CO;2-M.

¹ Institut für Organische Chemie der Universität, Richard-Willstätter-Allee 2, D-76128 Karlsruhe (Germany), Fax: (+49) 721-608-7652.

No abstract available

Keywords: Enzyme inhibitors; Neuraminic acids; Rational design; Sialyltransferases; Transition state analogues.