Inter- or Intramolecular Carbometalation of Nonactivated Alkynes by Zirconacyclopentanes in the Presence of Copper Chloride

Yuanhong Liu; Baojian Shen; Martin Kotora; Tamotsu Takahashi

doi:10.1002/(SICI)1521-3773(19990401)38:7<949::AID-ANIE949>3.0.CO;2-C

Inter- or Intramolecular Carbometalation of Nonactivated Alkynes by Zirconacyclopentanes in the Presence of Copper Chloride

Angew Chem Int Ed Engl. 1999 Apr 1;38(7):949-952. doi: 10.1002/(SICI)1521-3773(19990401)38:7<949::AID-ANIE949>3.0.CO;2-C.

Authors

Yuanhong Liu¹, Baojian Shen¹, Martin Kotora¹, Tamotsu Takahashi¹

Affiliation

¹ Catalysis Research Center and Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060 (Japan), Fax: (+81) 11-706-3274.

PMID: 29711870
DOI: 10.1002/(SICI)1521-3773(19990401)38:7<949::AID-ANIE949>3.0.CO;2-C

Abstract

Five- and six-membered carbocyles 2 and 3 can be obtained from zirconacyclopentanes of type 1 by a novel carbometalation with nonactivated alkynes in the presence of CuCl (see reaction scheme).

Keywords: Alkynes; Copper; Cyclizations; Metalations; Zirconium.