Successful Treatment of Growing Teratoma Syndrome of the Lung by Surgical Resection: A Case Report and Literature Review

Anticancer Res. 2018 May;38(5):3115-3118. doi: 10.21873/anticanres.12571.


Growing teratoma syndrome (GTS) of the lung is extremely rare, and there are very few reports on this condition. This is a case report of GTS of the lung that was successfully treated by resection. A 19-year-old man, who had been diagnosed with a testicular tumor, lung metastases and left hilar lymph node metastasis, underwent surgical resection for left testicular cancer. After orchiectomy and chemotherapy, the patient was successfully treated with wedge resection of the right upper lobe and left upper lobectomy. In conclusion, the current case suggests that some patients with GTS might be successfully treated by surgical resection.

Keywords: Growing teratoma syndrome; lung metastases; surgery.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Male
  • Neoplasms, Germ Cell and Embryonal / drug therapy
  • Neoplasms, Germ Cell and Embryonal / pathology*
  • Neoplasms, Germ Cell and Embryonal / surgery
  • Orchiectomy
  • Pneumonectomy
  • Syndrome
  • Teratoma / drug therapy
  • Teratoma / secondary*
  • Teratoma / surgery*
  • Testicular Neoplasms / drug therapy
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / surgery
  • Young Adult

Supplementary concepts

  • Testicular Germ Cell Tumor