Perforated duodenal ulcers after Roux-Y Gastric Bypass

Am J Emerg Med. 2018 Aug;36(8):1525.e1-1525.e3. doi: 10.1016/j.ajem.2018.04.057. Epub 2018 Apr 25.


Even though the incidence of complicated peptic ulcer disease (PUD) has decreased in the last decades, it remains a condition with a significant mortality. Whilst diagnosis and treatment of PUD in morbidly obese patients can be challenging, patients with excluded segments - such as after Roux-Y Gastric Bypass (RYGB) - present an even greater problem, as the subsequent altered anatomy impedes the common modalities used for diagnostic and therapeutic measures. We report the cases of two patients after RYGB with perforated duodenal ulcers in the intention to highlight problems regarding diagnosis and treatment. Patients with perforation after RYGB usually present without signs of hollow organ perforation in clinical examination but also in computed tomography scans. Diagnostic laparoscopy was performed to address the discrepancy between pain and non-diagnostic examinations. An aggressive approach in case of unexplained symptoms in these patients is not only justified but mandatory.

Keywords: Duodenal ulcer; Gastric bypass; Morbid obesity; Peptic ulcer perforation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Duodenal Ulcer / complications*
  • Female
  • Gastric Bypass / adverse effects*
  • Humans
  • Laparoscopy
  • Middle Aged
  • Obesity, Morbid / surgery*
  • Peptic Ulcer Perforation / diagnostic imaging
  • Peptic Ulcer Perforation / etiology*
  • Peptic Ulcer Perforation / surgery
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / etiology*
  • Postoperative Complications / surgery
  • Reoperation
  • Tomography, X-Ray Computed