Motor Proteins

Cold Spring Harb Perspect Biol. 2018 May 1;10(5):a021931. doi: 10.1101/cshperspect.a021931.


Myosin motors power movements on actin filaments, whereas dynein and kinesin motors power movements on microtubules. The mechanisms of these motor proteins differ, but, in all cases, ATP hydrolysis and subsequent release of the hydrolysis products drives a cycle of interactions with the track (either an actin filament or a microtubule), resulting in force generation and directed movement.

Publication types

  • Review

MeSH terms

  • Actin Cytoskeleton / metabolism
  • Adenosine Triphosphate / metabolism
  • Biological Transport / physiology
  • Dyneins / physiology*
  • Dyneins / ultrastructure
  • Kinesin / physiology*
  • Kinesin / ultrastructure
  • Models, Biological
  • Models, Molecular
  • Myosins / physiology*
  • Myosins / ultrastructure


  • Adenosine Triphosphate
  • Myosins
  • Dyneins
  • Kinesin