Type II and III Selective Fetal Growth Restriction: Perinatal Outcomes of Expectant Management and Laser Ablation of Placental Vessels

Clinics (Sao Paulo). 2018:73:e210. doi: 10.6061/clinics/2018/e210. Epub 2018 Apr 26.

Abstract

Objectives: To describe the perinatal outcomes of type II and III selective fetal growth restriction (sFGR) in monochorionic-diamniotic (MCDA) twin pregnancies treated with expectant management or laser ablation of placental vessels (LAPV).

Methods: Retrospective analysis of cases of sFGR that received expectant management (type II, n=6; type III, n=22) or LAPV (type II, n=30; type III, n=9). The main outcomes were gestational age at delivery and survival rate.

Results: The smaller fetus presented an absent/reversed "a" wave in the ductus venosus (arAWDV) in all LAPV cases, while none of the expectant management cases presented arAWDV. The median gestational age at delivery was within the 32nd week for expectant management (type II and III) and for type II LAPV, and the 30th week for type III LAPV. The rate of at least one twin alive at hospital discharge was 83.3% and 90.9% for expectant management type II and III, respectively, and 90% and 77.8% for LAPV type II and III, respectively.

Conclusion: LAPV in type II and III sFGR twins with arAWDV in the smaller fetus seems to yield outcomes similar to those of less severe cases that received expectant management.

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Fetal Death
  • Fetal Growth Retardation / mortality*
  • Fetal Growth Retardation / surgery
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Laser Therapy / methods*
  • Laser Therapy / mortality
  • Middle Aged
  • Perinatal Death
  • Placenta / blood supply
  • Placenta / surgery*
  • Pregnancy
  • Pregnancy Outcome*
  • Pregnancy, Twin*
  • Retrospective Studies
  • Survival Rate
  • Twins, Monozygotic
  • Ultrasonography, Prenatal
  • Young Adult