[Related Immunologic Mechanisms of Chronic Prostatitis: Advances in Studies]

Zhonghua Nan Ke Xue. 2017 Jul;23(7):652-655.
[Article in Chinese]


Chronic prostatitis is a common male disease with a high incidence rate and a serious impact on the patients' quality of life. The pathogenesis of chronic prostatitis remains unclear though it is considered to be possibly related to infection, inflammation, and abnormal pelvic nerve muscle activity. Recently, a growing number of studies have reported immune imbalance and changes of inflammatory cytokines in patients with chronic prostatitis as well as a close correlation of abnormal immune response with the occurrence of diseases, pelvic pain symptoms, mental symptoms, hyperalgesia, and so on. This review summarizes the latest advances in the studies of immunologic mechanisms of chronic prostatitis.


Keywords: CD4+ T lymphocyte; immune imbalance; immunologic mechanism; chronic prostatitis.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Cytokines / blood*
  • Humans
  • Hyperalgesia / immunology
  • Male
  • Pelvic Pain / immunology
  • Prostatitis / blood
  • Prostatitis / immunology*
  • Quality of Life


  • Cytokines