[Immunosuppressive therapy in dogs and cats. Properties of drugs and their use in various immune-mediated diseases]

Tierarztl Prax Ausg K Kleintiere Heimtiere. 2018 Apr;46(2):105-118. doi: 10.15654/TPK-180274. Epub 2018 May 4.
[Article in German]


Veterinarians are regularly faced with the diagnosis and therapy of immune-mediated diseases. More frequently occurring immune-mediated diseases are immune-mediated hemolytic anemia, immunemediated thrombocytopenia and polyarthritis. Glucocorticoids are commonly used as first-line treatment because of their availability, efficacy and rapid action. Nevertheless, some patients do not respond to glucocorticoid therapy alone. Others require a rapid dose reduction because of severe side effects from glucocorticoid treatment. These patients benefit from adjuvant therapies. Ciclosporin preparations are licensed for use in veterinary medicine. The use of azathioprine, mycophenolate mofetil and human immunoglobulin therapy has also been documented. This article describes the mode of action of certain immunosuppressive agents and their use in selected diseases from recent literature.

Publication types

  • Review

MeSH terms

  • Anemia, Hemolytic, Autoimmune / drug therapy
  • Anemia, Hemolytic, Autoimmune / immunology
  • Anemia, Hemolytic, Autoimmune / veterinary
  • Animals
  • Cat Diseases / drug therapy*
  • Cat Diseases / immunology
  • Cats
  • Dog Diseases / drug therapy*
  • Dog Diseases / immunology
  • Dogs
  • Immune System Diseases / drug therapy
  • Immune System Diseases / veterinary*
  • Immunosuppressive Agents / therapeutic use*
  • Thrombocytopenia / drug therapy
  • Thrombocytopenia / immunology
  • Thrombocytopenia / veterinary


  • Immunosuppressive Agents