High Rate of Discontinuation May Diminish PrEP Coverage Among Young Men Who Have Sex with Men

AIDS Behav. 2018 Nov;22(11):3645-3648. doi: 10.1007/s10461-018-2125-2.

Abstract
in En , Spanish

Understanding pre-exposure prophylaxis (PrEP) discontinuation is key to maximizing its effectiveness at the individual and population levels. Data came from the RADAR cohort study of MSM aged 16-29 years, 2015-2017. Participants included those who reported past 6-month PrEP use and discontinued its use by the interview date. Of the 197 participants who had used PrEP in the past 6 months, 65 discontinued use. Primary reasons for PrEP discontinuation included trouble getting to doctor's appointments (14, 21.5%) and issues related to insurance coverage or loss (13, 20.0%). Few (21%) who discontinued spoke to their doctor first, which has important implications for future long acting formulations.

Es importante entender la interrupción en el uso de PrEP para maximizar su efectividad a nivel individual y poblacional. Los datos proceden de RADAR, un estudio de cohorte de hombres que tienen sexo con hombres entre 16-29 años de edad. Se incluyeron participantes que reportaron haber usado PrEP en los últimos seis meses que posteriormente descontinuaron su uso. De los 197 participantes que usaron PrEP en los últimos 6 meses, 65 habían dejado de usar PrEP. Dentro de los motivos principales por los cuales dejaron de usar PrEP se encuentran dificultades para llegar a consultas médicas (14, 21.5%) y otras dificultades relacionadas con la cobertura o pérdida de seguro médico (13, 20.0%). Pocos (21%) indicaron haber consultado la descontinuacion de PrEP con su médico, lo cual presenta implicaciones importantes con respecto a futuras formulaciones de acción prolongada.

Keywords: Discontinuation; HIV; PrEP; YMSM.

MeSH terms

  • Adolescent
  • Adult
  • Anti-HIV Agents / administration & dosage*
  • Cohort Studies
  • HIV Infections / prevention & control*
  • HIV Infections / psychology
  • Homosexuality, Male / psychology*
  • Humans
  • Insurance Coverage
  • Longitudinal Studies
  • Male
  • Patient Acceptance of Health Care / psychology*
  • Pre-Exposure Prophylaxis*
  • Safe Sex
  • Sexual Behavior / psychology
  • Sexual Partners / psychology
  • Young Adult

Substances

  • Anti-HIV Agents