Outcome of focused pre-Ramadan education on metabolic and glycaemic parameters in patients with type 2 diabetes mellitus

Diabetes Metab Syndr. 2018 Sep;12(5):761-767. doi: 10.1016/j.dsx.2018.04.036. Epub 2018 Apr 25.

Abstract

Background: Ramadan fasting is associated with the risk of acute complications including hypoglycaemia. Therefore, patients' education before Ramadan and follow up during Ramadan is essential for safe fasting.

Objectives: To evaluate the effect of pre-Ramadan education program on biochemical parameters and the risk of hypoglycaemia in patients with type 2 diabetes mellitus.

Methods: A prospective interventional controlled design was carried out on 320 Muslim patients with type 2 diabetes. They were divided into 2 groups; the control group (n = 200) who received standard diabetic care and the intervention group (n = 120) who received focused individualized diabetic education sessions before Ramadan. The study was carried out on 3 phases (before, during and after Ramadan). Post-education change of hypoglycaemia risk and biochemical parameters during Ramadan fasting were the primary outcomes.

Results: Fasting blood glucose decreased significantly during, and after Ramadan in both groups (P < 0.001). Hypoglycaemia during fasting occurred in 4.1% of patients in the intervention group vs. 19.5% in the control group. Post Ramadan reduction of HbA1c < 7% increased statistically significantly in the intervention group (from 20.8% of patients before Ramadan to 55.8% after Ramadan). Low-density lipoprotein cholesterol decreased in the intervention group (P = 0.024). The body weight of the patients did not significantly change in both groups.

Conclusion: There was a significant impact of pre-Ramadan educational program on reduction of hypoglycaemic risk and other acute complications, reduction of low-density lipoprotein cholesterol and improvement of high-density lipoprotein cholesterol. Therefore, it is recommended for the fasting patients especially those with high and very high risk during Ramadan.

Keywords: Diabetes; Education; Egypt; Hypoglycaemia; Ramadan fasting.

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / metabolism*
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / ethnology*
  • Diabetes Mellitus, Type 2 / therapy
  • Fasting / blood*
  • Female
  • Follow-Up Studies
  • Glycemic Index / physiology
  • Humans
  • Hypoglycemia / blood
  • Hypoglycemia / ethnology
  • Hypoglycemia / prevention & control
  • Islam*
  • Male
  • Middle Aged
  • Patient Education as Topic / methods*
  • Patient Education as Topic / trends
  • Prospective Studies
  • Religion
  • Risk Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Blood Glucose