Abstract
Three unusual cases of Down's syndrome inheritance are presented which permit supposing that microstructural chromosome aberrations in parents may induce not only a structural imbalance of chromosomal material in progeny, but also a numerical imbalance.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Child, Preschool
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Chromosome Aberrations
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Chromosome Banding
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Down Syndrome / genetics*
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Down Syndrome / pathology
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Female
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Humans
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Infant
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Karyotyping
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Lymphocytes / ultrastructure
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Male
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Metaphase
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Phenotype