Mucinous Cystadenocarcinoma of the Breast: Report of 2 Cases Including One With Long-Term Local Recurrence

Int J Surg Pathol. 2018 Dec;26(8):749-757. doi: 10.1177/1066896918775810. Epub 2018 May 10.

Abstract

Primary mucinous cystadenocarcinoma (MCA) of breast is an exceedingly rare tumor with histologic resemblance to MCA arising in ovary, pancreas, and gastrointestinal tract. In this article, we present 2 additional cases of MCA of breast, one highlighting the diagnostic challenges of a rare entity that may potentially lead to unnecessary chemotherapy and the second case presenting with recurrence after 8 years of primary surgical excision defying the indolent behavior reported in the literature. To our knowledge, this is the first reported instance of such behavior.

Keywords: breast; cystadenocarcinoma; mucinous; rare; recurrence.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis*
  • Breast / diagnostic imaging
  • Breast / pathology*
  • Breast / surgery
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Cystadenocarcinoma, Mucinous / diagnostic imaging
  • Cystadenocarcinoma, Mucinous / pathology*
  • Cystadenocarcinoma, Mucinous / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Mammography
  • Mastectomy, Segmental
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / pathology*

Substances

  • Biomarkers, Tumor