The correlation of the degree of abnormal sperm morphology using strict criteria and pregnancy rates following intrauterine insemination (IUI)

Clin Exp Obstet Gynecol. 2017;44(2):183-184.


Objective: To determine the effect of extremely low sperm morphology on pregnancy rates following intrauterine insemination (IUI) where all other semen parameters were normal.

Materials and methods: Retrospective review of all IUI cycles over a two-year period on infertile women age ≤ 35 where all parameters, but morphology had to be normal. The data were evaluated according to seven levels of percentage of normal morphology (NM): 0, 1, 2, 3, 4, 5, and ≥ 6%.

Results: The percent live delivery was 9.5, 16.7, 8.8, 16.1, 11.4, 12.3, and 10.9%.

Conclusions: Morphology of 0% or 1% did not seem to impair pregnancy rates following IUI. More studies are needed but should include determining the confounding effect of the type of morphologic abnormality.

MeSH terms

  • Adult
  • Female
  • Fertilization in Vitro
  • Humans
  • Infertility, Female / therapy*
  • Insemination, Artificial, Homologous / methods*
  • Male
  • Parturition
  • Pregnancy
  • Pregnancy Rate
  • Retrospective Studies
  • Spermatozoa / pathology*
  • Statistics as Topic