Elevated free androgen index as an indicator of polycystic ovaries in oligomenorrhoea without obesity or hirsuties

Ann Clin Biochem. 1988 Jul:25 ( Pt 4):346-9. doi: 10.1177/000456328802500403.

Abstract

A group of oligomenorrhoeic women without obesity or hirsuties was investigated with high-resolution ultrasound, laparoscopy and biochemical parameters. In this series, polycystic ovaries (PCO), as defined by ultrasound and laparoscopy, are a common cause of oligomenorrhoea in women without the classic symptoms, and were strongly associated with an elevated free androgen index (FAI). Despite an elevated FAI, these women were not hirsute, It would seem reasonable to include a FAI in the investigation of the oligomenorrhoeic woman, along with the more 'standard' tests, such as thyroid function and a prolactin level.

MeSH terms

  • Adult
  • Androgens / blood*
  • Female
  • Hirsutism / complications
  • Humans
  • Laparoscopy
  • Menstruation Disturbances / diagnosis*
  • Obesity / complications
  • Oligomenorrhea / blood
  • Oligomenorrhea / complications
  • Oligomenorrhea / diagnosis*
  • Ovary / pathology
  • Polycystic Ovary Syndrome / blood
  • Polycystic Ovary Syndrome / diagnosis*
  • Polycystic Ovary Syndrome / pathology
  • Sex Hormone-Binding Globulin / analysis
  • Testosterone / blood
  • Ultrasonography

Substances

  • Androgens
  • Sex Hormone-Binding Globulin
  • Testosterone