Sex in Plasmodium falciparum: Silence Play between GDV1 and HP1

Trends Parasitol. 2018 Jun;34(6):450-452. doi: 10.1016/ Epub 2018 May 8.


Understanding how malaria parasites commit to sexual development is key to the development of transmission-blocking strategies. Recent work by Filarsky and colleagues extends our understanding of the molecular mechanisms driving this process by characterizing an early factor in gametocytogenesis, and showing how this fits neatly into our current knowledge of sexual commitment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Comment

MeSH terms

  • Chromosomal Proteins, Non-Histone*
  • Malaria, Falciparum / parasitology
  • Plasmodium falciparum*


  • Chromosomal Proteins, Non-Histone