Post-polio syndrome and the late effects of poliomyelitis: Part 2. treatment, management, and prognosis

Muscle Nerve. 2018 Dec;58(6):760-769. doi: 10.1002/mus.26167. Epub 2018 Aug 23.


Post-polio syndrome (PPS) is characterized by new muscle weakness and/or muscle fatigability that occurs many years after the initial poliomyelitis illness. An individualized approach to rehabilitation management is critical. Interventions may include rehabilitation management strategies, adaptive equipment, orthotic equipment, gait/mobility aids, and a variety of therapeutic exercises. The progression of muscle weakness in PPS is typically slow and gradual; however, there is also variability in both the natural history of weakness and functional prognosis. Further research is required to determine the effectiveness of selected medical treatment. Muscle Nerve 58:760-769, 2018.

Keywords: biomechanics; late effects of poliomyelitis; poliomyelitis; post-polio syndrome; rehabilitation.

Publication types

  • Review

MeSH terms

  • Disease Management*
  • Disease Progression
  • Humans
  • Poliomyelitis / complications*
  • Postpoliomyelitis Syndrome* / diagnosis
  • Postpoliomyelitis Syndrome* / etiology
  • Postpoliomyelitis Syndrome* / therapy
  • Prognosis