Nasal fibroscopy as a routine screening procedure of sinonasal adenocarcinoma of woodworkers: French longitudinal case study

Head Neck. 2018 Oct;40(10):2193-2198. doi: 10.1002/hed.25315. Epub 2018 May 13.

Abstract

Background: The purpose of this study was to assess the relevancy of flexible nasoendoscopy as a routine screening procedure of sinonasal adenocarcinoma among people occupationally exposed to wood dust.

Methods: This study included woodworkers, occupationally exposed to wood dust. Evaluations were scheduled at the time of inclusion (T0) and after a 2-year period (T1). A questionnaire was used for standardized data collection. The score was based on anatomic landmarks on each side that are parts of the olfactory clefts: the area of middle turbinate, the anterior part of the olfactory cleft, the top of the choanal arch, the spheno-ethmoidal recess, the posterior part of the olfactory cleft, and the middle part of the olfactory cleft.

Results: A total of 965 nasoendoscopies (T0+T1) were performed. Olfactory clefts were visualized in 72% of the cases. Nasoendoscopies revealed pathological findings in 33.6% of cases: polyps, thick nasal secretion aspect, mucous edema, retractile scars and synechia, crusts, mucous erythema, and growth. One case of carcinoma was confirmed. Adverse effects (epistaxis, blood mark on the endo-sheath, sneezing, or rhinorrhea) after the medical procedure occurred in 30% of cases without severe complications.

Conclusion: Flexible nasoendoscopy offers meaningful efficacy and a promising safety profile, and, therefore, could become the new cornerstone of the routine screening procedure of sinonasal adenocarcinoma among woodworkers.

Keywords: medical follow-up; nasal fibroscopy; olfactory clefts; sinonasal adenocarcinoma; woodworkers.

Publication types

  • Multicenter Study
  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / diagnosis
  • Dust*
  • Early Detection of Cancer / methods
  • Endoscopy*
  • Female
  • France
  • Humans
  • Longitudinal Studies
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Nose Neoplasms / diagnosis*
  • Occupational Diseases / diagnosis*
  • Occupational Exposure / adverse effects
  • Paranasal Sinus Neoplasms / diagnosis*
  • Visual Analog Scale
  • Wood / adverse effects*

Substances

  • Dust