Analysis of weight changes after left gastric artery embolization in a cancer-naive population

Diagn Interv Radiol. Mar-Apr 2018;24(2):94-97. doi: 10.5152/dir.2018.17412.

Abstract

Purpose: We aimed to evaluate weight changes after left gastric artery (LGA) embolization in a retrospective cancer-naive cohort.

Methods: A retrospective study was conducted to identify patients who underwent LGA embolization for gastrointestinal bleeding (GI). Patients with known cancer diagnoses at the time of LGA embolization were excluded. Pre- and postprocedure weights were assessed. Statistical analysis was performed using paired t-test and Wilcoxon signed-rank test.

Results: A total of 39 patients were identified. In 21 patients who had documented pre- and postprocedural weights, a median of 16.3 kg weight loss (P = 0.045) was observed over a median time of 12 months (range, 2-72). In patients who had pre- and postprocedure endoscopies (n=6), 2 had worsening ulcers following LGA embolization and 4 had stable or no abnormal findings.

Conclusion: Our preliminary observation suggests that LGA embolization is well tolerated and results in unintended weight loss. Larger studies are needed to confirm these preliminary findings.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arteries / surgery*
  • Body Mass Index
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / methods*
  • Female
  • Gastrointestinal Hemorrhage / pathology
  • Gastrointestinal Hemorrhage / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neoplasms / complications*
  • Neoplasms / pathology
  • Retrospective Studies
  • Stomach / blood supply*
  • Stomach / pathology
  • Stomach / surgery
  • Stomach Ulcer / epidemiology
  • Stomach Ulcer / etiology
  • Treatment Outcome
  • Weight Loss / physiology