Current Evidence-Based Understanding of the Epidemiology, Prevention, and Treatment of Atrial Fibrillation

Curr Probl Cardiol. 2018 Jun;43(6):241-283. doi: 10.1016/j.cpcardiol.2017.06.001. Epub 2017 Jun 7.


Atrial fibrillation (AF) is the most common atrial arrhythmia in adults worldwide. As medical advancements continue to contribute to an ever-increasing aging population, the burden of atrial fibrillation on the modern health care system continues to increase. Therapies are also evolving, for treatment of the arrhythmia itself, and stroke risk mitigation. Internists and cardiologists alike are, in most instances, the frontline contact for AF patients, and would benefit from remaining facile in their understanding of care options. To continue to deliver high-quality care to this expanding patient group, an updated, concise review for the clinician is prudent. This article provides a comprehensive summary of the current epidemiology and pathophysiology of AF, as well as contemporary procedural therapeutic options.

Publication types

  • Review

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use
  • Anticoagulants / therapeutic use
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / epidemiology*
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / therapy*
  • Catheter Ablation / methods
  • Comorbidity
  • Evidence-Based Medicine / methods
  • Humans
  • Risk Reduction Behavior
  • Stroke / etiology
  • Stroke / prevention & control


  • Anti-Arrhythmia Agents
  • Anticoagulants