Drug-Induced Sleep-Disordered Breathing and Ventilatory Impairment

Sleep Med Clin. 2018 Jun;13(2):161-168. doi: 10.1016/j.jsmc.2018.03.003.


This article describes current knowledge about drug entities that have the potential to induce, aggravate, or modify sleep-disordered breathing. The drug effects on sleep-disordered breathing may vary by patient age, gender, and comorbidity. In general, the clinical relevance of drug-induced sleep-disordered breathing is increasing in sleep medicine and the evidence in the field is growing in parallel.

Keywords: Anabolic steroids; Baclofen; Benzodiazepines; Growth hormone; Hypoventilation; Opiates; Sleep apnea.

Publication types

  • Review

MeSH terms

  • Animals
  • Benzodiazepines / adverse effects
  • Drug-Related Side Effects and Adverse Reactions*
  • Humans
  • Respiration
  • Sleep Apnea Syndromes / chemically induced*


  • Benzodiazepines