A Primer for the Rat Genome Database (RGD)

Methods Mol Biol. 2018;1757:163-209. doi: 10.1007/978-1-4939-7737-6_8.

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu ) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.

Keywords: Database; Gene; Genomics; Ontology; Quantitative trait locus; Rat.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Computational Biology / methods
  • Data Analysis
  • Data Mining
  • Databases, Genetic*
  • Gene Ontology
  • Genome*
  • Genomics* / methods
  • Phenotype
  • Quantitative Trait Loci
  • Rats
  • Search Engine
  • Software
  • User-Computer Interface
  • Web Browser