Interactive web-based identification and visualization of transcript shared sequences

Genomics. 2019 Jul;111(4):860-862. doi: 10.1016/j.ygeno.2018.05.010. Epub 2018 May 12.

Abstract

We have developed TraC (Transcript Consensus), a web-based tool for detecting and visualizing shared sequences among two or more mRNA transcripts such as splice variants. Results including exon-exon boundaries are returned in a highly intuitive, data-rich, interactive plot that permits users to explore the similarities and differences of multiple transcript sequences. The online tool (http://labs.pathology.jhu.edu/nauen/trac/) is free to use. The source code is freely available for download (https://github.com/nauenlab/TraC).

Keywords: Alternative splicing; RNA; Splice variant; Visualization.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Consensus Sequence*
  • Humans
  • RNA Splicing*
  • RNA, Messenger / chemistry
  • RNA, Messenger / genetics*
  • Sequence Analysis, RNA / methods*
  • Software*
  • Transcriptome

Substances

  • RNA, Messenger