Endoscopic diagnosis of a goblet cell carcinoid tumour of the appendix

BMJ Case Rep. 2018 May 15;2018:bcr2017223298. doi: 10.1136/bcr-2017-223298.


Primary malignancies of the appendix are rare. Of these, less than 5% are goblet cell carcinoid (GCC) tumours. The majority of GCC present with findings of acute appendicitis or advanced peritoneal spread. We describe a rare presentation of GCC as subtle mucosal abnormality of the appendiceal orifice seen on colonoscopy performed for iron-deficiency anaemia. Biopsies were interpreted as adenocarcinoma; however, final surgical pathology confirmed GCC of the appendix with caecal involvement. The patient recovered well from surgery, anaemia resolved and follow-up did not show metastatic disease.

Keywords: colon cancer; endoscopy; general surgery; gi bleeding.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anemia, Iron-Deficiency / etiology
  • Appendiceal Neoplasms / complications
  • Appendiceal Neoplasms / pathology*
  • Appendiceal Neoplasms / surgery
  • Biopsy
  • Carcinoid Tumor / complications
  • Carcinoid Tumor / pathology*
  • Carcinoid Tumor / surgery
  • Colectomy
  • Colonoscopy*
  • Humans
  • Incidental Findings
  • Liver / diagnostic imaging
  • Magnetic Resonance Imaging
  • Male