Transition to chronic pain: opportunities for novel therapeutics

Nat Rev Neurosci. 2018 Jul;19(7):383-384. doi: 10.1038/s41583-018-0012-5.


Although chronic pain is one of the most important medical problems facing society, there has been very limited progress in the development of novel therapies for this condition. Here, we discuss high-impact research priorities to reduce the number of people transitioning from acute to chronic intractable pain.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acute Pain / physiopathology*
  • Animals
  • Brain / physiopathology*
  • Chronic Pain / etiology
  • Chronic Pain / physiopathology*
  • Clinical Trials as Topic
  • Disease Progression*
  • Humans
  • Neurons / physiology
  • Pain Management*