A Little Fiber Goes a Long Way

Patricia A C Castillo; Timothy W Hand

doi:10.1016/j.immuni.2018.05.001

A Little Fiber Goes a Long Way

Immunity. 2018 May 15;48(5):844-846. doi: 10.1016/j.immuni.2018.05.001.

Authors

Patricia A C Castillo¹, Timothy W Hand²

Affiliations

¹ Richard King Mellon Foundation Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Department of Pediatrics and Immunology, University of Pittsburgh, Pittsburgh, PA 15224, USA.
² Richard King Mellon Foundation Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Department of Pediatrics and Immunology, University of Pittsburgh, Pittsburgh, PA 15224, USA. Electronic address: timothy.hand@chp.edu.

PMID: 29768170
DOI: 10.1016/j.immuni.2018.05.001

Abstract

In this issue of Immunity, Trompette et al. (2018) show that dietary fiber and short chain fatty acids reduce influenza A virus-associated immunopathology by enhancing CD8⁺ T cell effector function and by promoting the differentiation of alternatively activated macrophages.

Publication types

Comment

MeSH terms

CD8-Positive T-Lymphocytes*
Dietary Fiber
Immunity
Influenza A virus*

Substances

Dietary Fiber