An anti-NMDA receptor encephalitis mimicking an HIV encephalitis

Clin Immunol. 2018 Aug;193:10-11. doi: 10.1016/j.clim.2018.05.003. Epub 2018 May 14.

Abstract

The incidence of HIV associated neurocognitive disorders (HAND) were reduced with the use of antiretroviral therapy. In case of neuropsychiatric symptoms, after elimination of all infections, auto-immune encephalitis could be evocated as a differential diagnosis. We describe a case of anti-N-Methyl-d-Aspartate receptor encephalitis in an HIV-1 infected woman.

Keywords: Anti-NMDA receptor antibodies; Autoimmune encephalitis; HIV.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / diagnosis
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / drug therapy
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / immunology*
  • Anxiety
  • Autoantibodies / cerebrospinal fluid*
  • Diagnosis, Differential
  • Electrocardiography
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy
  • HIV Infections / immunology*
  • HIV-1 / physiology*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Memory Disorders
  • Middle Aged
  • Receptors, N-Methyl-D-Aspartate / immunology*
  • Recovery of Function
  • Sleep Initiation and Maintenance Disorders

Substances

  • Autoantibodies
  • Immunoglobulins, Intravenous
  • Receptors, N-Methyl-D-Aspartate