Depression in perinatally HIV-infected pregnant women compared to non-perinatally HIV-infected and HIV-uninfected pregnant women

AIDS Care. 2018 Sep;30(9):1168-1172. doi: 10.1080/09540121.2018.1476659. Epub 2018 May 18.


"Depression (as noted in chart by a physician)" was compared between HIV infected pregnant women and controls. Perinatally HIV-infected (PHIV), non-perinatally HIV-infected (NPHIV), and HIV-uninfected (HIV-U) pregnant women were all compared using a logistic regression model. Overall, HIV-infected women had higher rates of depression than HIV-U, with PHIV women demonstrating a clinically and statistically significant increased risk compared to HIV-U women [adjusted OR: 15.9, 95% CI = 1.8-143.8]. Future studies in larger populations are warranted to confirm these findings and further elucidate mental health outcomes of PHIV and NPHIV pregnant women.

Keywords: Perinatally acquired HIV; depression; pregnancy.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Case-Control Studies
  • Cohort Studies
  • Depression / complications*
  • Female
  • HIV Infections / complications
  • HIV Infections / psychology*
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / psychology*
  • Young Adult