CCR7 fuels and LFA-1 grips

Nat Immunol. 2018 Jun;19(6):516-518. doi: 10.1038/s41590-018-0118-y.


Naïve T cells migrate rapidly through the lymph node. A high-resolution look at the chemokine receptor CCR7 and integrin LFA-1 reveals T cells remain highly responsive to their microenvironment by instantaneous tuning of chemokine-regulated actin flow and integrin-regulated adhesion.

Publication types

  • Comment

MeSH terms

  • Actins
  • Chemokines
  • Friction
  • Lymphocyte Function-Associated Antigen-1*
  • T-Lymphocytes*


  • Actins
  • Chemokines
  • Lymphocyte Function-Associated Antigen-1