Fighting obesity: Non-pharmacological interventions

Clin Nutr ESPEN. 2018 Jun;25:50-55. doi: 10.1016/j.clnesp.2018.04.005. Epub 2018 Apr 18.


The abnormal or excessive fat accumulation that impairs health is one of the criteria that fulfills obesity. According to epidemiological data, obesity has become a worldwide public health problem that in turn would trigger additional pathologies such as cardiorespiratory dysfunctions, cancer, gastrointestinal disturbances, depression, sleep disorders, just to mention a few. Then, the search for a therapeutical intervention aimed to prevent and manage obesity has been the focus of study during the last years. As one can assume, the increased prevalence of obesity has translated to search of efficient pharmaceuticals designed to manage this health issue. However, to further complicate the scenario, scientific literature has described that obesity is the result of interaction between multiple events. Therefore, pharmacological approaches have faced a serious challenge for develop the adequate treatment. Here, we argue that a wide range of non-pharmacological/invasive techniques can be used to manage obesity, such as diets, cognitive behavioral interventions, exercise and transcranial direct current stimulation. Combining these techniques may allow improving quality of life of obese patients.

Keywords: Diets; Intervention; Obesity; Physical activity; Therapy; Weight.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Cognitive Behavioral Therapy*
  • Diet, Healthy
  • Exercise
  • Feeding Behavior
  • Health Knowledge, Attitudes, Practice
  • Healthy Lifestyle*
  • Humans
  • Nutritional Status
  • Obesity / epidemiology
  • Obesity / physiopathology
  • Obesity / psychology
  • Obesity / therapy*
  • Quality of Life
  • Risk Factors
  • Severity of Illness Index
  • Transcranial Magnetic Stimulation*
  • Treatment Outcome
  • Weight Loss*