Impact Exerted by Nutritional Risk Screening on Clinical Outcome of Patients with Esophageal Cancer

Biomed Res Int. 2018 Mar 27:2018:7894084. doi: 10.1155/2018/7894084. eCollection 2018.

Abstract

Objective: Preoperative nutritional status of patients is closely associated with their recovery after the surgery. This study aims to ascertain the impact exerted by the nutritional risk screening on clinical outcome of patients with esophageal cancer.

Methods: 160 patients with esophageal cancer aged over 60, having got therapy at the First Hospital of Jilin University from Jun 2016 to Feb 2017 were evaluated by adopting the NRS2002. 80 cases of patients got active therapy of nutritional support, and the other patients not supported nutritionally were selected as the control group. The comparison was drawn between two groups in serum albumin, serum immunoglobulin, postoperative complications, hospitalization, and hospitalization expenses.

Results: For all the patients, in 3 and 7 days after the surgery, the serum albumin in the nutritionally supported group outstripped that in group without nutritional support (P < 0.05) regardless of the nutritional risk. For the patients in the risk of nutrition, the IgA in the nutritionally supported group outstripped that of group without nutritional support (P < 0.05) in 3 and 7 days before the surgery, and the serum IgG outstripped that of the group without nutritional support in 1 and 3 days before the surgery (P < 0.05). In terms of the patients in the risk of nutrition, the average hospitalization of nutritionally supported group was shorter (P < 0.05), and the average hospitalization expenses were lower compared with those of the group without nutritional support. And for the patients in no risk, the hospitalization expenses of supported group surmounted those of group without nutritional support (P < 0.05), whereas the average hospitalization took on no statistic difference (P > 0.05).

Conclusion: For the patients in the risk of nutrition, preoperative nutritional support can facilitate the nutritional status and immunization-relative result after surgery, which shall also decrease the average hospitalization and hospitalization cost.

MeSH terms

  • Aged
  • Esophageal Neoplasms / diet therapy*
  • Esophageal Neoplasms / surgery
  • Female
  • Hospitalization / economics
  • Humans
  • Immunoglobulin A / blood
  • Immunoglobulin G / blood
  • Male
  • Middle Aged
  • Nutrition Assessment
  • Nutritional Status*
  • Nutritional Support*
  • Postoperative Complications
  • Preoperative Care*
  • Risk
  • Serum Albumin / analysis
  • Treatment Outcome

Substances

  • Immunoglobulin A
  • Immunoglobulin G
  • Serum Albumin