Trainability of hemodynamic parameters: A near-infrared spectroscopy based neurofeedback study

Biol Psychol. 2018 Jul;136:168-180. doi: 10.1016/j.biopsycho.2018.05.009. Epub 2018 May 18.

Abstract

We investigated the trainability of the hemodynamic response as assessed with near-infrared spectroscopy (NIRS) during one neurofeedback (NF) session. Forty-eight participants were randomly assigned to four different groups that tried to either increase or decrease oxygenated (oxy-Hb) or deoxygenated hemoglobin (deoxy-Hb) over the inferior frontal gyrus during imagery of swallowing movements. Deoxy-Hb could be successfully up-regulated while oxy-Hb could be successfully down-regulated during NF. Participants were not able to down-regulate deoxy-Hb or to up-regulate oxy-Hb. These results show that the natural course of oxy- and deoxy-Hb during movement imagery can be reinforced by providing real-time feedback of the corresponding NIRS parameter since deoxy-Hb generally increases and oxy-Hb decreases during imagery of swallowing. Furthermore, signal-to-noise ratio of deoxy-Hb but not of oxy-Hb improved during training. Our results provide new insights into the trainability of the hemodynamic response as assessed with NIRS and have an impact on the application of NIRS-based real-time feedback.

Keywords: Dysphagia; Motor imagery; NIRS; Neurofeedback; Swallowing.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological / physiology*
  • Adult
  • Deglutition / physiology
  • Female
  • Hemodynamics / physiology*
  • Hemoglobins / metabolism
  • Humans
  • Imagery, Psychotherapy / methods*
  • Male
  • Neurofeedback / physiology*
  • Oxygen / metabolism
  • Prefrontal Cortex / physiology
  • Spectroscopy, Near-Infrared / methods*

Substances

  • Hemoglobins
  • Oxygen