Vaccines, inspiring innovation in health

Vaccine. 2018 Nov 19;36(48):7430-7437. doi: 10.1016/j.vaccine.2018.05.035. Epub 2018 May 19.

Abstract

This report covers the topics of pandemics, epidemics and partnerships, including regulatory convergence initiatives, new technologies and novel vaccines, discussed by leading public and private sector stakeholders at the 18th Annual General Meeting (AGM) of the Developing Countries Vaccine Manufacturers' Network (DCVMN). Contributions of Gavi and the vaccine industry from emerging countries to the growing global vaccine market, by improving the supply base from manufacturers in developing countries and contributing to 58% of doses, were highlighted. The Coalition for Epidemic Preparedness Innovations (CEPI), the International Vaccine Institute (IVI) and others reported on new strategies to ensure speedy progress in preclinical and clinical development of innovative vaccines for future MERS, Zika or other outbreak response. Priorities for vaccine stockpiling, to assure readiness during emergencies and to prevent outbreaks due to re-emerging diseases such as yellow fever, cholera and poliomyelitis, were outlined. The role of partnerships in improving global vaccine access, procurement and immunization coverage, and shared concerns were reviewed. The World Health Organization (WHO) and other international collaborating partners provided updates on the Product, Price and Procurement database, the prequalification of vaccines, the control of neglected tropical diseases, particularly the new rabies elimination initiative, and regulatory convergence proposals to accelerate vaccine registration in developing countries. Updates on supply chain innovations and novel vaccine platforms were presented. The discussions enabled members and partners to reflect on efficiency of research & development, supply chain tools and trends in packaging technologies improving delivery of existing vaccines, and allowing a deeper understanding of the current public-health objectives, industry financing, and global policies, required to ensure optimal investments, alignment and stability of vaccine supply in developing countries.

Keywords: Developing countries; Epidemic; Procurement; Stockpiling; Technology; Vaccine manufacturing.

Publication types

  • Congress
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Developing Countries*
  • Disease Eradication
  • Epidemics / prevention & control
  • Global Health*
  • Humans
  • Immunization Programs* / economics
  • Immunization Programs* / statistics & numerical data
  • International Cooperation
  • Neglected Diseases / prevention & control
  • Poliomyelitis / prevention & control
  • Private Sector
  • Public Health / economics
  • Public Health / legislation & jurisprudence
  • Vaccination Coverage
  • Vaccines*
  • World Health Organization
  • Zika Virus Infection / prevention & control

Substances

  • Vaccines