Abstract
Neurodegenerative disease Alzheimer's disease (AD) is attracting growing concern because of an increasing patient population among the elderly. Tea consumption is considered a natural complementary therapy for neurodegenerative diseases. In this paper, epidemiological studies on the association between tea consumption and the reduced risk of AD are reviewed and the anti-amyloid effects of related bioactivities in tea are summarized. Future challenges regarding the role of tea in preventing AD are also discussed.
Keywords:
Alzheimer’s disease; Camellia sinensis; Parkinson’s disease; caffeine; epigallocatechin gallate (EGCG); theanine.
MeSH terms
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Age Factors
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Aged
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Aged, 80 and over
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Alzheimer Disease / epidemiology
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Alzheimer Disease / metabolism
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Alzheimer Disease / pathology
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Alzheimer Disease / prevention & control*
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Amyloid beta-Peptides / antagonists & inhibitors*
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Amyloid beta-Peptides / metabolism
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Animals
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Brain / drug effects*
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Brain / metabolism
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Brain / pathology
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Camellia sinensis / chemistry
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Cognition / drug effects
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Humans
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Memory / drug effects
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Middle Aged
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Nerve Degeneration
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Neuroprotective Agents / isolation & purification
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Neuroprotective Agents / therapeutic use*
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Oxidative Stress / drug effects
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Plant Extracts / isolation & purification
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Plant Extracts / therapeutic use*
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Prognosis
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Protective Factors
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Recommended Dietary Allowances
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Risk Factors
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Tea*
Substances
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Amyloid beta-Peptides
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Neuroprotective Agents
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Plant Extracts
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Tea