Association of Tea Consumption with Risk of Alzheimer's Disease and Anti-Beta-Amyloid Effects of Tea

Nutrients. 2018 May 22;10(5):655. doi: 10.3390/nu10050655.

Abstract

Neurodegenerative disease Alzheimer's disease (AD) is attracting growing concern because of an increasing patient population among the elderly. Tea consumption is considered a natural complementary therapy for neurodegenerative diseases. In this paper, epidemiological studies on the association between tea consumption and the reduced risk of AD are reviewed and the anti-amyloid effects of related bioactivities in tea are summarized. Future challenges regarding the role of tea in preventing AD are also discussed.

Keywords: Alzheimer’s disease; Camellia sinensis; Parkinson’s disease; caffeine; epigallocatechin gallate (EGCG); theanine.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / epidemiology
  • Alzheimer Disease / metabolism
  • Alzheimer Disease / pathology
  • Alzheimer Disease / prevention & control*
  • Amyloid beta-Peptides / antagonists & inhibitors*
  • Amyloid beta-Peptides / metabolism
  • Animals
  • Brain / drug effects*
  • Brain / metabolism
  • Brain / pathology
  • Camellia sinensis / chemistry
  • Cognition / drug effects
  • Humans
  • Memory / drug effects
  • Middle Aged
  • Nerve Degeneration
  • Neuroprotective Agents / isolation & purification
  • Neuroprotective Agents / therapeutic use*
  • Oxidative Stress / drug effects
  • Plant Extracts / isolation & purification
  • Plant Extracts / therapeutic use*
  • Prognosis
  • Protective Factors
  • Recommended Dietary Allowances
  • Risk Factors
  • Tea*

Substances

  • Amyloid beta-Peptides
  • Neuroprotective Agents
  • Plant Extracts
  • Tea